LO #3. Describe two findings of myocardial ischemia that can be observed on ECG. Correlate these ECG findings with action potentials at different locations in the conduction pathways of the heart. A 60-year-old man is being evaluated for myocardial ischemia. ECG reveals ST-segment depression. Changes in the action potential in what location of the heart are most consistent with these ECG findings? A. Ventricular muscle B. Atrial muscle C. SA node D. Purkinje fibers