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(Solved): 1. Leiomyomas are neoplasms that form due to expansion of smooth muscle cells. They often form in ...



1. Leiomyomas are neoplasms that form due to expansion of smooth muscle cells. They often form in the uterus. Most leiomyomas

1. Leiomyomas are neoplasms that form due to expansion of smooth muscle cells. They often form in the uterus. Most leiomyomas carry specific mutations in the MED12 gene. a. Leiomyomas typically maintain a highly differentiated phenotype and do not spread. Based on these characteristics, would you argue that leiomyomas are benign or malignant growths? b. Are leiomyomas tumours? Why/why not? c. Are leiomyomas cancer? Why/why not? d. Based on the description, do you think leiomyomas arise from a single cell (clonal growth)? Substantiate your answer citing the difference between clonal and non-clonal growths.


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