(Solved): 1 Multiple Choice 4 points Which answer best describes characteristics of regulated necrotic cell de ...

1 Multiple Choice 4 points Which answer best describes characteristics of regulated necrotic cell death? A. Severe oxidative stress causing mitochondrial dysfunction and ATP depletion initiates mitochondrial permeability transition (MPT)-driven regulated necrosis. B. The key cellular organelles involved in regulated necrosis are the mitochondria and the nucleus C. Severe DNA damage in the endoplasmic reticulum causes Poly ADP-Ribose Polymerase 1 (PARP1) inactivation and initiates parthanatos. D. A and B are correct. E. All of the above are correct.