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Consider a tissue of thickness ? and mass diffusivity ???? surrounded on both sides by fluids 1 and 2. A species S is diffusing across this tissue and has concentrations ????1 ???? and ????2 ???? in the fluids on the two sides of the tissue. The solubility of species S inside the tissue is different from its solubility in the fluids. We therefore define partition coefficients: ?1F = ????1 ???? /????1 ???? and ?2???? = ????2 ???? /????2 ???? , where ????1 ???? and ????2 ???? are the concentrations of species S in the tissue at the interfaces 1 and 2, respectively.
Hence ?iF < 1 means that S is less soluble in the tissue than in fluid ????, and vice versa.
a) Solve the diffusion equation with appropriate boundary conditions to find the concentration of species S across the tissue at steady state
b) Write down an expression for the mass-transfer coefficient across the tissue in terms of ????1 ???? , ????2 ???? ,????, ?, and the partition coefficients.