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(Solved): Explain these 6 mechanisms of aplastic anemia: Destruction of HSCs Senescence and apoptosis of HSC ...



Explain these 6 mechanisms of aplastic anemia: Destruction of HSCs Senescence and apoptosis of HSCs due to genetic mutations Ineffective hematopoiesis cause by HSC mutation or vitamin B12 deficiency Disruption of BM microenvironment Disruption of growth factors Infiltration of marrow space by abnormal cells



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