(Solved): For questions 3 through 6 , let's revisit our randomized controlled trial to determine the effect o ...

For questions 3 through 6 , let's revisit our randomized controlled trial to determine the effect of a novel red blood cell growth factor (HemoglobinatorQ) versus standard epoetin alfa (Epogen $$?$$ ) in cancer patients undergoing myelosuppressive chemotherapy on hemoglobin $$(\mathrm{Hb})$$ blood levels that was included in Group Exercise 3. All patients in the trial had $$\mathrm{Hb}$$ levels between 9 and $$10\mathrm{g}/\mathrm{dL}$$ at baseline, i.e. at risk for a blood transfusion. The investigators are now interested in determining how many patients in each treatment arm were, at 12 weeks, in the transfusion zone ( $$\mathrm{Hb}<9\mathrm{g}/\mathrm{dL}$$ ), how many patients in each treatment arm were in the anemic range $$(9.0?12.0\mathrm{g}/\mathrm{dL})$$, and how many patients in each treatment arm had $$\mathrm{Hb}$$ levels > $$12\mathrm{g}/\mathrm{dL}$$ ? Consider only the $$\mathrm{Hb}$$ levels at 12 weeks; the baseline $$\mathrm{Hb}$$ does not need to be considered as all patients were between 9 and $$10\mathrm{g}/\mathrm{dL}$$ at baseline. 3. What would the contingency table look like? a. $$1\times 2$$ b. $$1\times 3$$ c. $$2\times 2$$ d. $$2\times 3$$ 4. Which statistical test would you use to analyze the data? a. $${\mathrm{X}}^2$$ test of independence with Yates' correction. b. $$X^2$$ test of independence c. Fisher's exact test d. $$X^2$$ goodness-of-fit test e. McNemar's $$X^2$$ test 5. How many degrees of freedom (df) are there in this analysis? How did you calculate this? a. 1 b. 2 c. 3 d. 4 e. 5 f. 6 g. 7 h. 8 6. An ardent team member argues that the study had two time points (baseline/week 0,12 weeks) and should use McNemar $$X^2$$ test? What is your reply? a. Yes, the team member is right. b. No, the team member is wrong. c. The team member is neither right nor wrong.