hich statement applies to a client who is on long-term corticosteroid therapy after an renalectomy and admitted to the surgical intensive care unit after being involved in a otor vehicle crash? The dosage of steroids will have to be tapered down slowly to prevent acute adrenal crisis. Steroid therapy will need to be increased to avert a life-threatening crisis. Osteoporosis secondary to long-term corticosteroids increases fracture risk. The client is at risk for Cushing syndrome if taking long-term corticosteroid therapy.