Name Ch. 19: Erythrocyte Turnover Renna: Biology 110 The average lifespan of an
_(21)
(red blood cell) ranges from
90-120
days. The
_(10)
, or rupture, of an erythrocyte in the bloodstream occurs to only a small percentage of the total erythrocyte number. When this occurs, hemoglobin that is not broken down, circulates to the and is eliminated in the . When abnormally large numbers of erythrocytes breakdown in the blood, the urine turns red or brown in a condition known as ; intact red blood cells in the urine is known as . Most worn-out red blood cells are phagocytized in the liver,
(20)
_ or red bone marrow by a . The _ (19)__ is stripped from the hemoglobin and transported back to by a carrier protein, , for reuse. from the globin chains are either metabolized by the cell or released into the blood for use by other cells. The _ is broken down in the macrophage to , a green color, and then , an orange-yellow pigment. It is then released into the blood and transported to the for excretion as into the . As bilirubin enters the large intestine, it is broken down further by bacteria into what will eventually become, when exposed to oxygen, and _ and ultimately eliminated in . Abnormally high rates of hemolysis or liver disease may result in the accumulation of bilirubin in the skin and the sclera ("white's") of the eyes in a condition known as __(6)_.