(Solved): Question \#1: Inheritance pattern in this pedigree? Question \#2: how can you explain the inherita ...

Question \#1: Inheritance pattern in this pedigree? Question \#2: how can you explain the inheritance pattern in this family? Question $$\#3$$ a. Write the genotypes of the individuals b.If individuals III- 1 and III-8 marry, what is the probability that their first child will be sick? a.Write the genotypes b.If individuals 1 and 2 marry, what is the probability that their first child will be sick? - PKU is a human hereditary disease resulting from inability of the body to process the chemical phenylalanine (contained in protein that we eat). - It is caused by a recessive allele with simple Mendelian inheritance. - A couple wants to have children. The man has a sister with PKU and the woman has a brother with PKU. There are no other known cases in their families. - Discuss the probability that their first child will have PKU ? Possibilities: AA $$\times AA?AA$$ : oll cluldren wilhe healthy $$AA\times AC?AA,Aa=11,60\%$$ $$Aa\times Aa?AA$$, Aa, aa: $$1/4$$ sick