(Solved): Which of the following observations is consistent with the development of tolerance of the isolated ...

Which of the following observations is consistent with the development of tolerance of the isolated guinea-pig ileum to an opiate agonist? Select one: The twitch responses to electrical stimulation are inhibited initially by a high dose of morphine, but increase gradually over the period of continued exposure The twitch responses to electrical stimulation are inhibited initially by a high dose of morphine, and continue to decrease over a period of continued exposure The twitch responses to electrical stimulation are increased initially by a high dose of morphine, but decrease gradually over a period of continued exposure The twitch responses to electrical stimulation are increased initially by a high dose of morphine, and continue to increase over the period of continued exposure The twitch responses to electrical stimulation are increased initially by a high dose of morphine, and remain constant over the period of continued exposure