(Solved): Which of the following observations would be consistent with the development of tolerance to morphin ...

Which of the following observations would be consistent with the development of tolerance to morphine within the Caco-2 cell based assay? Select one: Increased concentration of morphine needed to reduce cAMP levels after pre-treatment with naloxone Decreased concentration of morphine needed to reduce cAMP levels after pre-treatment with morphine Decreased concentration of morphine needed to reduce cAMP levels after pre-treatment with naloxone Increased concentration of morphine needed to reduce cAMP levels after pre-treatment with morphine