Which of the following statements about receptor tyrosine kinases (RTKs) is true? Please consider only normal/unmutated RTKs. (Select all that apply.)
a. RTKs are active as monomers.
b. RTKs undergoes a conformational change when they bind their signal protein. This can unveil molecular complementarity that allows an RTK to dimerize.
c. Dimerized RTKs phosphorylate one another. Phosphorylated RTKs gain molecular complementarity for additional signaling proteins.
d. Phosphate groups can be removed from proteins by a kinase. Thus, kinases can inactivate phosphorylated RTKs.