Which of the following statements is true? Choose one:
?A. Kais the dissociation constant, which is the equilibrium constant that expresses the protein-ficand complex concentration as the numerator in the equilibrium expression.
?B. Ligand
xand Ligand
Yboth bind to Protein
Z. The interaction of Ligand
xwith Protein
Zhas a
K=0.2mM. while the interaction of Ligand Y with Protein Z has a
K,0.6mM. Ligand X therefore has a higher affinity for Proteln ? than Gready
?C. Ligand X and Ligand Y both bind to Protein Z . The interaction of Ligand X with Protein Z has a
Ki=0.2mM, while the interaction of Ligand Y with Protein Z has a Ka
=0.6mM. Ligand X therefore has a higher affinity for Protein Z than Liend Y.
?